Thimmasettappa Thippeswamy Selected Research

Isoflurophate (DFP)

1/2022	Characterization of Cortical Glial Scars in the Diisopropylfluorophosphate (DFP) Rat Model of Epilepsy.
1/2022	DFP-Induced Status Epilepticus Severity in Mixed-Sex Cohorts of Adult Rats Housed in the Same Room: Behavioral and EEG Comparisons.
12/2021	Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Disease Modifier in the Rat DFP Model: Sex Differences, Neurobehavior, Gliosis, Neurodegeneration, and Nitro-Oxidative Stress.
1/2021	Differential Impact of Severity and Duration of Status Epilepticus, Medical Countermeasures, and a Disease-Modifier, Saracatinib, on Brain Regions in the Rat Diisopropylfluorophosphate Model.
11/2020	Sex as a biological variable in the rat model of diisopropylfluorophosphate-induced long-term neurotoxicity.
11/2020	Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model.
1/2020	Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model.

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Thimmasettappa Thippeswamy Research Topics

Disease

15	Status Epilepticus (Complex Partial Status Epilepticus) 01/2022 - 11/2012
13	Seizures (Absence Seizure) 01/2022 - 06/2008
10	Epilepsy (Aura) 01/2022 - 11/2012
10	Gliosis 01/2022 - 11/2012
6	Neuroinflammatory Diseases 11/2019 - 01/2015
2	Brain Injuries (Brain Injury) 01/2021 - 01/2020
2	Disease Progression 01/2021 - 06/2017
2	Temporal Lobe Epilepsy 01/2021 - 01/2016
1	Cicatrix (Scar) 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Parkinson Disease (Parkinson's Disease) 01/2021
1	Drug Resistant Epilepsy 06/2017
1	Wounds and Injuries (Trauma) 06/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2015
1	Peripheral Nerve Injuries 02/2010

Drug/Important Bio-Agent (IBA)

11	Kainic Acid (Kainate)IBA 01/2021 - 06/2008
7	Isoflurophate (DFP)FDA Link 01/2022 - 01/2020
4	OrganophosphatesIBA 01/2022 - 11/2020
4	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2022 - 01/2016
4	saracatinibIBA 12/2021 - 01/2018
4	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 11/2012
3	Nerve AgentsIBA 01/2022 - 01/2021
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2010
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2017
3	NitrogenIBA 01/2021 - 01/2015
3	Diazepam (Valium)FDA LinkGeneric 01/2021 - 11/2012
3	Oxygen (Dioxygen)IBA 01/2021 - 01/2015
3	CytokinesIBA 01/2021 - 01/2020
2	3-nitrotyrosineIBA 12/2021 - 01/2020
2	src-Family KinasesIBA 12/2021 - 01/2018
2	Proto-Oncogene Proteins c-fynIBA 01/2021 - 01/2021
2	OximesIBA 01/2021 - 01/2020
2	Atropine FDA LinkGeneric 01/2021 - 01/2020
2	Serum AlbuminIBA 01/2021 - 01/2016
2	Cholinergic Agents (Cholinergics)IBA 01/2021 - 11/2020
2	ChemokinesIBA 11/2020 - 01/2020
2	Pharmaceutical PreparationsIBA 11/2019 - 01/2016
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2019 - 02/2010
2	Protein Isoforms (Isoforms)IBA 01/2019 - 06/2017
2	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 11/2012 - 06/2008
1	Chondroitin Sulfate ProteoglycansIBA 01/2022
1	Complement C3 (C3 Complement)IBA 01/2022
1	FilaminsIBA 01/2021
1	NADPH Oxidase 2IBA 01/2021
1	Cathepsin BIBA 01/2021
1	Fibrinogen (Factor I)FDA Link 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2021
1	Midazolam (Versed)FDA LinkGeneric 01/2021
1	NADP (NADPH)IBA 01/2021
1	SomanIBA 01/2021
1	VimentinIBA 01/2021
1	Galectin 1 (LGALS1)IBA 01/2021
1	Cystatin CIBA 01/2021
1	Interleukin-17 (Interleukin 17)IBA 11/2020
1	LeptinIBA 11/2020
1	InterleukinsIBA 11/2020
1	Interleukin-2 (IL2)IBA 11/2020
1	Interleukin-6 (Interleukin 6)IBA 11/2020
1	NitritesIBA 11/2020
1	Blood Proteins (Serum Proteins)IBA 11/2020
1	AcetylcholinesteraseIBA 11/2020
1	ParvalbuminsIBA 01/2020
1	Pentylenetetrazole (Metrazol)IBA 01/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 11/2019
1	HSP27 Heat-Shock ProteinsIBA 11/2019
1	Glial Fibrillary Acidic ProteinIBA 11/2019
1	Biological ProductsIBA 11/2019
1	Hyaluronan ReceptorsIBA 11/2019
1	Phosphotransferases (Kinase)IBA 01/2018
1	DisulfidesIBA 06/2017
1	HMGB1 Protein (HMG1)IBA 06/2017
1	Mitochondrial DNA (mtDNA)IBA 01/2015
1	AntioxidantsIBA 01/2015
1	SynaptophysinIBA 11/2012
1	Arginine (L-Arginine)FDA Link 11/2012
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2010
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2010
1	Soluble Guanylyl CyclaseIBA 06/2008

Therapy/Procedure

2	Therapeutics 01/2020 - 11/2019
1	Electrodes (Electrode) 01/2021
1	Implanted Electrodes 01/2021
1	Behavior Control 01/2018